Forensic Analysis · Healthcare / Pharmaceuticals / Biotech · as of Sep 25, 2026
Syndax Pharmaceuticals Inc (SNDX)
A forensic read on Syndax Pharmaceuticals Inc built from its complete SEC filings — financial-health screens, earnings quality, red flags and a price-aware rating. Reproducible math, not opinion.
F · Poor — capital at risk
Forensic grade
Distress
Financial health
-4.1
Distress distance
Clean
Earnings quality
3
Forensic signals
-7.0
P / E (ttm)
-441.6%
ROE
$1.6B
Market cap
0.00%
Dividend yield
627.8%
Revenue growth
This free snapshot doesn't read filing or proxy text, so the auditor-quality and governance checks that can lower a grade were not evaluated (red flags, auditor quality, say on pay, board independence, going concern, valuation). Those checks only ever lower a grade, so the full analysis can land below the grade above but never above it — treat it as the most favourable reading, not the settled one.
Syndax Pharmaceuticals Inc earns an F (Poor — capital at risk) forensic quality grade, and its balance-sheet distress test reads -4.1, placing it in the Distress zone. 3 forensic signals were flagged in its latest SEC filings, led by return on invested capital.
What the filings flag
-34.5%
FY2025
Return on invested capital.Return on invested capital is -34.5% in the latest fiscal year and rising across FY2023–FY2025 from -70.0%. After-tax operating profit was ($182M) in FY2023 and ($216M) in FY2025, with operating income at -1434.4% of revenue in FY2024 and -158.4% in FY2025. The capital base behind it grew +141% across FY2023–FY2025, from $259M to $625M, and the return did not fall doing it, so the dollars added over that window earned at least the -70.0% the older base was already earning.
+11.0%/yr
FY2023–FY2025
Share-count dilution.Diluted share count changed +23% over the last 2 years to FY2025 (+11.0%/yr). The count is growing: more stock was issued than repurchased over this window, so aggregate results grew faster than their per-share equivalents. That's ~11.0% shaved off per-share growth every year — total profit has to grow that much just to keep earnings-per-share flat, and a stake held since FY2023 has been diluted ~19%.
28% of rev
FY2025
Stock-based comp load.Stock-based compensation ran 28% of revenue in FY2025 — about $0.55 per diluted share. No cash left the business to pay it, which is why operating cash flow adds it back. Net of repurchases the diluted count still rose about 11.4% a year, and the rate is falling. Stock compensation is one source of that issuance; acquisition consideration, equity raises, convertibles and other employee plans also net into the count, and these figures do not separate them.
Key fundamentals
Latest Revenue$172.4M
Revenue Growth YoY+627.8%
Net Margin-165.6%
Free Cash Flow-$323.2M
Return on Equity-441.6%
Debt / Equity5.42x
The forensic grade and screens above are free — no account needed. Want the AI investment read on top — the 0–100 rating, thesis, bull-vs-bear, red flags and the 12-month scenario, written from Syndax Pharmaceuticals Inc's actual 10-K/10-Q/8-K filings?